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Nomura et al., 2016), and others also showed a role of glycolysis in fueling the TCA cycle for mitochondrial respiration in M2-polarized macrophages dependent on the mTORC2 and STAT6 pathways towards IRF4 activation ( 4.3.2 Fatty acid synthesis FAS has been identified to be necessary for M1 induction (Wei et al., 2016)

Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, et al

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7.4.1.4 Insulin-like growth factor-1 (IGF-1) IGF-1 is a potent neurotrophic factor that is involved in the regulation of neuronal growth and survival

250 Obesity significantly impacts B cell function